Intraocular Pressure-Lowering Effect of Latanoprost Is Hampered by Defective Cervical Lymphatic Drainage
Identifieur interne : 000468 ( Main/Exploration ); précédent : 000467; suivant : 000469Intraocular Pressure-Lowering Effect of Latanoprost Is Hampered by Defective Cervical Lymphatic Drainage
Auteurs : Young Kook Kim [Corée du Sud] ; Kyeong Ik Na [Corée du Sud] ; Jin Wook Jeoung [Corée du Sud] ; Ki Ho Park [Corée du Sud]Source :
- PLoS ONE [ 1932-6203 ] ; 2017.
Abstract
To evaluate whether defects in cervical lymphatic drainage influence the intraocular pressure (IOP)-lowering effect of latanoprost in patients with primary open-angle glaucoma (POAG) who have undergone unilateral radical neck dissection (uRND).
We enrolled (1) bilateral POAG patients who had started (bilateral) latanoprost (0.005%) monotherapy prior to their uRND and (2) treatment-naïve, bilateral glaucoma suspects (GSs) who had undergone the same surgery. We compared the eyes ipsilateral to the uRND with their fellow eyes in terms of the changes in IOP between the baseline (prior to the uRND) and the follow-up visits (1, 3, and 6 months after the uRND).
The study involved 22 eyes of 11 POAG patients and 14 eyes of 7 GSs. In the POAG patients, IOP had increased significantly after surgery in the eyes ipsilateral to the uRND (from 14.7±1.4mmHg to 17.1±2.2mmHg; P = 0.007). Interestingly, in the eyes contralateral to the uRND, IOP had not changed significantly after surgery (from 14.2±1.8mmHg to 14.4±2.0mmHg; P = 0.826). In GSs, the eyes ipsilateral to the uRND did not differ significantly from their fellow eyes in terms of post-operative IOP change (ipsilateral value: 0.3±0.5mmHg, fellow eyes: -0.1±0.7mmHg; P = 0.242).
In the POAG patients, IOP had increased significantly in the eyes ipsilateral to the uRND. However, it had not changed significantly in the eyes contralateral to the surgery or in the eyes of the GSs. These findings suggest that, latanoprost works, at least in part, by enhancing outflow from the aqueous humor via the uveolymphatic pathway.
Url:
DOI: 10.1371/journal.pone.0169683
PubMed: 28081184
PubMed Central: 5231387
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Intraocular Pressure-Lowering Effect of Latanoprost Is Hampered by Defective Cervical Lymphatic Drainage</title><author><name sortKey="Kim, Young Kook" sort="Kim, Young Kook" uniqKey="Kim Y" first="Young Kook" last="Kim">Young Kook Kim</name><affiliation wicri:level="3"><nlm:aff id="aff001"><addr-line>Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea</addr-line></nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Ophthalmology, Seoul National University Hospital, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff002"><addr-line>Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea</addr-line></nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Ophthalmology, Seoul National University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Na, Kyeong Ik" sort="Na, Kyeong Ik" uniqKey="Na K" first="Kyeong Ik" last="Na">Kyeong Ik Na</name><affiliation wicri:level="3"><nlm:aff id="aff001"><addr-line>Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea</addr-line></nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Ophthalmology, Seoul National University Hospital, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Jeoung, Jin Wook" sort="Jeoung, Jin Wook" uniqKey="Jeoung J" first="Jin Wook" last="Jeoung">Jin Wook Jeoung</name><affiliation wicri:level="3"><nlm:aff id="aff001"><addr-line>Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea</addr-line></nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Ophthalmology, Seoul National University Hospital, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff002"><addr-line>Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea</addr-line></nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Ophthalmology, Seoul National University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Park, Ki Ho" sort="Park, Ki Ho" uniqKey="Park K" first="Ki Ho" last="Park">Ki Ho Park</name><affiliation wicri:level="3"><nlm:aff id="aff001"><addr-line>Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea</addr-line></nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Ophthalmology, Seoul National University Hospital, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff002"><addr-line>Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea</addr-line></nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Ophthalmology, Seoul National University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author></titleStmt><publicationStmt><idno 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type="wicri:Area/Main/Exploration">000468</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Intraocular Pressure-Lowering Effect of Latanoprost Is Hampered by Defective Cervical Lymphatic Drainage</title><author><name sortKey="Kim, Young Kook" sort="Kim, Young Kook" uniqKey="Kim Y" first="Young Kook" last="Kim">Young Kook Kim</name><affiliation wicri:level="3"><nlm:aff id="aff001"><addr-line>Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea</addr-line></nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Ophthalmology, Seoul National University Hospital, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff002"><addr-line>Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea</addr-line></nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Ophthalmology, Seoul National University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Na, Kyeong Ik" sort="Na, Kyeong Ik" uniqKey="Na K" first="Kyeong Ik" last="Na">Kyeong Ik Na</name><affiliation wicri:level="3"><nlm:aff id="aff001"><addr-line>Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea</addr-line></nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Ophthalmology, Seoul National University Hospital, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Jeoung, Jin Wook" sort="Jeoung, Jin Wook" uniqKey="Jeoung J" first="Jin Wook" last="Jeoung">Jin Wook Jeoung</name><affiliation wicri:level="3"><nlm:aff id="aff001"><addr-line>Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea</addr-line></nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Ophthalmology, Seoul National University Hospital, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff002"><addr-line>Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea</addr-line></nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Ophthalmology, Seoul National University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Park, Ki Ho" sort="Park, Ki Ho" uniqKey="Park K" first="Ki Ho" last="Park">Ki Ho Park</name><affiliation wicri:level="3"><nlm:aff id="aff001"><addr-line>Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea</addr-line></nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Ophthalmology, Seoul National University Hospital, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff002"><addr-line>Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea</addr-line></nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Ophthalmology, Seoul National University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author></analytic><series><title level="j">PLoS ONE</title><idno type="eISSN">1932-6203</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="sec001"><title>Purpose</title><p>To evaluate whether defects in cervical lymphatic drainage influence the intraocular pressure (IOP)-lowering effect of latanoprost in patients with primary open-angle glaucoma (POAG) who have undergone unilateral radical neck dissection (uRND).</p></sec><sec id="sec002"><title>Methods</title><p>We enrolled (1) bilateral POAG patients who had started (bilateral) latanoprost (0.005%) monotherapy prior to their uRND and (2) treatment-naïve, bilateral glaucoma suspects (GSs) who had undergone the same surgery. We compared the eyes ipsilateral to the uRND with their fellow eyes in terms of the changes in IOP between the baseline (prior to the uRND) and the follow-up visits (1, 3, and 6 months after the uRND).</p></sec><sec id="sec003"><title>Results</title><p>The study involved 22 eyes of 11 POAG patients and 14 eyes of 7 GSs. In the POAG patients, IOP had increased significantly after surgery in the eyes ipsilateral to the uRND (from 14.7±1.4mmHg to 17.1±2.2mmHg; P = 0.007). Interestingly, in the eyes contralateral to the uRND, IOP had not changed significantly after surgery (from 14.2±1.8mmHg to 14.4±2.0mmHg; P = 0.826). In GSs, the eyes ipsilateral to the uRND did not differ significantly from their fellow eyes in terms of post-operative IOP change (ipsilateral value: 0.3±0.5mmHg, fellow eyes: -0.1±0.7mmHg; P = 0.242).</p></sec><sec id="sec004"><title>Conclusion</title><p>In the POAG patients, IOP had increased significantly in the eyes ipsilateral to the uRND. However, it had not changed significantly in the eyes contralateral to the surgery or in the eyes of the GSs. These findings suggest that, latanoprost works, at least in part, by enhancing outflow from the aqueous humor via the uveolymphatic pathway.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Heijl, A" uniqKey="Heijl A">A Heijl</name></author><author><name sortKey="Leske, Mc" uniqKey="Leske M">MC Leske</name></author><author><name sortKey="Bengtsson, B" uniqKey="Bengtsson B">B Bengtsson</name></author><author><name sortKey="Hyman, L" uniqKey="Hyman L">L Hyman</name></author><author><name sortKey="Bengtsson, B" uniqKey="Bengtsson B">B Bengtsson</name></author><author><name sortKey="Hussein, M" uniqKey="Hussein M">M Hussein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Leske, Mc" uniqKey="Leske M">MC Leske</name></author><author><name sortKey="Heijl, A" uniqKey="Heijl A">A Heijl</name></author><author><name sortKey="Hussein, M" uniqKey="Hussein M">M Hussein</name></author><author><name sortKey="Bengtsson, B" uniqKey="Bengtsson B">B Bengtsson</name></author><author><name sortKey="Hyman, L" uniqKey="Hyman L">L Hyman</name></author><author><name sortKey="Komaroff, E" uniqKey="Komaroff E">E Komaroff</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Goel, M" uniqKey="Goel M">M Goel</name></author><author><name sortKey="Picciani, Rg" uniqKey="Picciani R">RG Picciani</name></author><author><name sortKey="Lee, Rk" uniqKey="Lee R">RK Lee</name></author><author><name sortKey="Bhattacharya, Sk" uniqKey="Bhattacharya S">SK Bhattacharya</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yucel, Yh" uniqKey="Yucel Y">YH Yucel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yucel, Yh" uniqKey="Yucel Y">YH Yucel</name></author><author><name sortKey="Johnston, Mg" uniqKey="Johnston M">MG Johnston</name></author><author><name sortKey="Ly, T" uniqKey="Ly T">T Ly</name></author><author><name sortKey="Patel, M" uniqKey="Patel M">M Patel</name></author><author><name sortKey="Drake, B" uniqKey="Drake B">B Drake</name></author><author><name sortKey="Gumus, E" uniqKey="Gumus E">E Gumus</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tam, Al" uniqKey="Tam A">AL Tam</name></author><author><name sortKey="Gupta, N" uniqKey="Gupta N">N Gupta</name></author><author><name sortKey="Zhang, Z" uniqKey="Zhang Z">Z Zhang</name></author><author><name sortKey="Yucel, Yh" uniqKey="Yucel Y">YH Yucel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hollo, G" uniqKey="Hollo G">G Hollo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Poyer, Jf" uniqKey="Poyer J">JF Poyer</name></author><author><name sortKey="Millar, C" uniqKey="Millar C">C Millar</name></author><author><name sortKey="Kaufman, Pl" uniqKey="Kaufman P">PL Kaufman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thieme, H" uniqKey="Thieme H">H Thieme</name></author><author><name sortKey="Schimmat, C" uniqKey="Schimmat C">C Schimmat</name></author><author><name sortKey="Munzer, G" uniqKey="Munzer G">G Munzer</name></author><author><name sortKey="Boxberger, M" uniqKey="Boxberger M">M Boxberger</name></author><author><name sortKey="Fromm, M" uniqKey="Fromm M">M Fromm</name></author><author><name sortKey="Pfeiffer, N" uniqKey="Pfeiffer N">N Pfeiffer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lutjen Drecoll, E" uniqKey="Lutjen Drecoll E">E Lutjen-Drecoll</name></author><author><name sortKey="Tamm, E" uniqKey="Tamm E">E Tamm</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Richter, M" uniqKey="Richter M">M Richter</name></author><author><name sortKey="Krauss, Ah" uniqKey="Krauss A">AH Krauss</name></author><author><name sortKey="Woodward, Df" uniqKey="Woodward D">DF Woodward</name></author><author><name sortKey="Lutjen Drecoll, E" uniqKey="Lutjen Drecoll E">E Lutjen-Drecoll</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Crawford, K" uniqKey="Crawford K">K Crawford</name></author><author><name sortKey="Kaufman, Pl" uniqKey="Kaufman P">PL Kaufman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nilsson, Sf" uniqKey="Nilsson S">SF Nilsson</name></author><author><name sortKey="Sperber, Go" uniqKey="Sperber G">GO Sperber</name></author><author><name sortKey="Bill, A" uniqKey="Bill A">A Bill</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Johnston, Mg" uniqKey="Johnston M">MG Johnston</name></author><author><name sortKey="Gordon, Jl" uniqKey="Gordon J">JL Gordon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ohhashi, T" uniqKey="Ohhashi T">T Ohhashi</name></author><author><name sortKey="Mizuno, R" uniqKey="Mizuno R">R Mizuno</name></author><author><name sortKey="Ikomi, F" uniqKey="Ikomi F">F Ikomi</name></author><author><name sortKey="Kawai, Y" uniqKey="Kawai Y">Y Kawai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tam, Al" uniqKey="Tam A">AL Tam</name></author><author><name sortKey="Gupta, N" uniqKey="Gupta N">N Gupta</name></author><author><name sortKey="Zhang, Z" uniqKey="Zhang Z">Z Zhang</name></author><author><name sortKey="Yucel, Yh" uniqKey="Yucel Y">YH Yucel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Camras, Cb" uniqKey="Camras C">CB Camras</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alm, A" uniqKey="Alm A">A Alm</name></author><author><name sortKey="Stjernschantz, J" uniqKey="Stjernschantz J">J Stjernschantz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Scherer, Wj" uniqKey="Scherer W">WJ Scherer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Swartz, Ma" uniqKey="Swartz M">MA Swartz</name></author><author><name sortKey="Skobe, M" uniqKey="Skobe M">M Skobe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Swartz, Ma" uniqKey="Swartz M">MA Swartz</name></author><author><name sortKey="Hubbell, Ja" uniqKey="Hubbell J">JA Hubbell</name></author><author><name sortKey="Reddy, St" uniqKey="Reddy S">ST Reddy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Swartz, Ma" uniqKey="Swartz M">MA Swartz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wiig, H" uniqKey="Wiig H">H Wiig</name></author><author><name sortKey="Swartz, Ma" uniqKey="Swartz M">MA Swartz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bradbury, Mw" uniqKey="Bradbury M">MW Bradbury</name></author><author><name sortKey="Cole, Df" uniqKey="Cole D">DF Cole</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Krohn, J" uniqKey="Krohn J">J Krohn</name></author><author><name sortKey="Rodahl, E" uniqKey="Rodahl E">E Rodahl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Foldi, M" uniqKey="Foldi M">M Foldi</name></author><author><name sortKey="Csanda, E" uniqKey="Csanda E">E Csanda</name></author><author><name sortKey="Simon, M" uniqKey="Simon M">M Simon</name></author><author><name sortKey="Obal, F" uniqKey="Obal F">F Obal</name></author><author><name sortKey="Schneider, I" uniqKey="Schneider I">I Schneider</name></author><author><name sortKey="Dobranovics, I" uniqKey="Dobranovics I">I Dobranovics</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Casley Smith, Jr" uniqKey="Casley Smith J">JR Casley-Smith</name></author><author><name sortKey="Clodius, L" uniqKey="Clodius L">L Clodius</name></author><author><name sortKey="Foldi Borcsok, E" uniqKey="Foldi Borcsok E">E Foldi-Borcsok</name></author><author><name sortKey="Gruntzig, J" uniqKey="Gruntzig J">J Gruntzig</name></author><author><name sortKey="Foldi, M" uniqKey="Foldi M">M Foldi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yucel, Y" uniqKey="Yucel Y">Y Yucel</name></author><author><name sortKey="Gupta, N" uniqKey="Gupta N">N Gupta</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Unthank, Jl" uniqKey="Unthank J">JL Unthank</name></author><author><name sortKey="Hogan, Rd" uniqKey="Hogan R">RD Hogan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Amann Vesti, Br" uniqKey="Amann Vesti B">BR Amann-Vesti</name></author><author><name sortKey="Gitzelmann, G" uniqKey="Gitzelmann G">G Gitzelmann</name></author><author><name sortKey="Koppensteiner, R" uniqKey="Koppensteiner R">R Koppensteiner</name></author><author><name sortKey="Franzeck, Uk" uniqKey="Franzeck U">UK Franzeck</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Franzeck, Uk" uniqKey="Franzeck U">UK Franzeck</name></author><author><name sortKey="Spiegel, I" uniqKey="Spiegel I">I Spiegel</name></author><author><name sortKey="Fischer, M" uniqKey="Fischer M">M Fischer</name></author><author><name sortKey="Bortzler, C" uniqKey="Bortzler C">C Bortzler</name></author><author><name sortKey="Stahel, Hu" uniqKey="Stahel H">HU Stahel</name></author><author><name sortKey="Bollinger, A" uniqKey="Bollinger A">A Bollinger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shayan, R" uniqKey="Shayan R">R Shayan</name></author><author><name sortKey="Achen, Mg" uniqKey="Achen M">MG Achen</name></author><author><name sortKey="Stacker, Sa" uniqKey="Stacker S">SA Stacker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ohhashi, T" uniqKey="Ohhashi T">T Ohhashi</name></author><author><name sortKey="Olschowka, Ja" uniqKey="Olschowka J">JA Olschowka</name></author><author><name sortKey="Jacobowitz, Dm" uniqKey="Jacobowitz D">DM Jacobowitz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Harisinghani, Mg" uniqKey="Harisinghani M">MG Harisinghani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Foldi, M" uniqKey="Foldi M">M Foldi</name></author><author><name sortKey="Csanda, E" uniqKey="Csanda E">E Csanda</name></author><author><name sortKey="Zoltan, Ot" uniqKey="Zoltan O">OT Zoltan</name></author><author><name sortKey="Dobranovics, I" uniqKey="Dobranovics I">I Dobranovics</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hollo, G" uniqKey="Hollo G">G Hollo</name></author><author><name sortKey="Pap, G" uniqKey="Pap G">G Pap</name></author><author><name sortKey="Bagi, Zt" uniqKey="Bagi Z">ZT Bagi</name></author><author><name sortKey="Kovacsovics, B" uniqKey="Kovacsovics B">B Kovacsovics</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cross, Jm" uniqKey="Cross J">JM Cross</name></author><author><name sortKey="Girkin, Ca" uniqKey="Girkin C">CA Girkin</name></author><author><name sortKey="Owsley, C" uniqKey="Owsley C">C Owsley</name></author><author><name sortKey="Mcgwin, G" uniqKey="Mcgwin G">G McGwin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Parekh, As" uniqKey="Parekh A">AS Parekh</name></author><author><name sortKey="Mansouri, K" uniqKey="Mansouri K">K Mansouri</name></author><author><name sortKey="Weinreb, Rn" uniqKey="Weinreb R">RN Weinreb</name></author><author><name sortKey="Tafreshi, A" uniqKey="Tafreshi A">A Tafreshi</name></author><author><name sortKey="Korn, Bs" uniqKey="Korn B">BS Korn</name></author><author><name sortKey="Kikkawa, Do" uniqKey="Kikkawa D">DO Kikkawa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Krupin, T" uniqKey="Krupin T">T Krupin</name></author><author><name sortKey="Jacobs, Ls" uniqKey="Jacobs L">LS Jacobs</name></author><author><name sortKey="Podos, Sm" uniqKey="Podos S">SM Podos</name></author><author><name sortKey="Becker, B" uniqKey="Becker B">B Becker</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Corée du Sud</li></country><region><li>Région capitale de Séoul</li></region><settlement><li>Séoul</li></settlement></list><tree><country name="Corée du Sud"><region name="Région capitale de Séoul"><name sortKey="Kim, Young Kook" sort="Kim, Young Kook" uniqKey="Kim Y" first="Young Kook" last="Kim">Young Kook Kim</name></region><name sortKey="Jeoung, Jin Wook" sort="Jeoung, Jin Wook" uniqKey="Jeoung J" first="Jin Wook" last="Jeoung">Jin Wook Jeoung</name><name sortKey="Jeoung, Jin Wook" sort="Jeoung, Jin Wook" uniqKey="Jeoung J" first="Jin Wook" last="Jeoung">Jin Wook Jeoung</name><name sortKey="Kim, Young Kook" sort="Kim, Young Kook" uniqKey="Kim Y" first="Young Kook" last="Kim">Young Kook Kim</name><name sortKey="Na, Kyeong Ik" sort="Na, Kyeong Ik" uniqKey="Na K" first="Kyeong Ik" last="Na">Kyeong Ik Na</name><name sortKey="Park, Ki Ho" sort="Park, Ki Ho" uniqKey="Park K" first="Ki Ho" last="Park">Ki Ho Park</name><name sortKey="Park, Ki Ho" sort="Park, Ki Ho" uniqKey="Park K" first="Ki Ho" last="Park">Ki Ho Park</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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